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Ex vivo analysis platforms for monitoring amyloid precursor protein cleavage

Alzheimer’s disease (AD) is a progressive neurodegenerative brain disorder and the most common cause of dementia in the elderly. The presence of large numbers of senile plaques, neurofibrillary tangles, and cerebral atrophy is the characteristic feature of AD. Amyloid β peptide (Aβ), derived from th...

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Detalles Bibliográficos
Autores principales: Kamikubo, Yuji, Jin, Hao, Zhou, Yiyao, Niisato, Kazue, Hashimoto, Yoshie, Takasugi, Nobumasa, Sakurai, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852844/
https://www.ncbi.nlm.nih.gov/pubmed/36683852
http://dx.doi.org/10.3389/fnmol.2022.1068990