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Microbial metabolites indole derivatives sensitize mice to D-GalN/LPS induced-acute liver failure via the Tlr2/NF-κB pathway

INTRODUCTION: Acute liver failure (ALF) is a clinical condition with many causes, fast progression, and a poor prognosis. Previous research has indicated that microbial factors have a role in ALF, but a clear picture has yet to emerge. METHODS: To investigate the specific involvement of microbial me...

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Detalles Bibliográficos
Autores principales: Zhou, Ziyuan, Wang, Baohong, Pan, Xiaxia, Lv, Jiawen, Lou, Zhuoqi, Han, Yuqiu, Yao, Yuanyuan, Chen, Jun, Wang, Qiangqiang, Li, Lanjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852867/
https://www.ncbi.nlm.nih.gov/pubmed/36687651
http://dx.doi.org/10.3389/fmicb.2022.1103998