PDGF-BB is involved in HIF-1α/CXCR4/CXCR7 axis promoting capillarization of hepatic sinusoidal endothelial cells

BACKGROUND: The activation of HIF-1α/CXCR4 pathway in liver sinusoidal endothelial cells (LSECs) could downregulate CXCR7, leading to the capillarization of LSECs to promote hepatic fibrosis. However, the mechanism between CXCR4 and CXCR7 is still undefined. The aim is to investigate the role of PDG...

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Detalles Bibliográficos
Autores principales: Fang, Jing, Ji, Qiang, Gao, Siqi, Xiao, Zhun, Liu, Wei, Hu, Yonghong, Lv, Ying, Chen, Gaofeng, Mu, Yongping, Cai, Hong, Chen, Jiamei, Liu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852936/
https://www.ncbi.nlm.nih.gov/pubmed/36685431
http://dx.doi.org/10.1016/j.heliyon.2022.e12715

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852936/
https://www.ncbi.nlm.nih.gov/pubmed/36685431
http://dx.doi.org/10.1016/j.heliyon.2022.e12715

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