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PDGF-BB is involved in HIF-1α/CXCR4/CXCR7 axis promoting capillarization of hepatic sinusoidal endothelial cells
BACKGROUND: The activation of HIF-1α/CXCR4 pathway in liver sinusoidal endothelial cells (LSECs) could downregulate CXCR7, leading to the capillarization of LSECs to promote hepatic fibrosis. However, the mechanism between CXCR4 and CXCR7 is still undefined. The aim is to investigate the role of PDG...
Autores principales: | Fang, Jing, Ji, Qiang, Gao, Siqi, Xiao, Zhun, Liu, Wei, Hu, Yonghong, Lv, Ying, Chen, Gaofeng, Mu, Yongping, Cai, Hong, Chen, Jiamei, Liu, Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852936/ https://www.ncbi.nlm.nih.gov/pubmed/36685431 http://dx.doi.org/10.1016/j.heliyon.2022.e12715 |
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