Synopsis of the pharmacokinetics, pharmacodynamics, applications, and safety of firocoxib in horses

According to in vitro and in vivo investigations, firocoxib (FX), a second-generation coxib, is a highly selective COX-2 inhibitor in horses. With a COX-1/COX-2 IC(50) ratio of 643 in horses, FX spares the COX-1 inhibitory effects. It is approved for the treatment of musculoskeletal problems and lam...

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Detalles Bibliográficos
Autores principales: Fadel, Charbel, Giorgi, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852958/
https://www.ncbi.nlm.nih.gov/pubmed/36684818
http://dx.doi.org/10.1016/j.vas.2023.100286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852958/
https://www.ncbi.nlm.nih.gov/pubmed/36684818
http://dx.doi.org/10.1016/j.vas.2023.100286

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