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Synopsis of the pharmacokinetics, pharmacodynamics, applications, and safety of firocoxib in horses
According to in vitro and in vivo investigations, firocoxib (FX), a second-generation coxib, is a highly selective COX-2 inhibitor in horses. With a COX-1/COX-2 IC(50) ratio of 643 in horses, FX spares the COX-1 inhibitory effects. It is approved for the treatment of musculoskeletal problems and lam...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852958/ https://www.ncbi.nlm.nih.gov/pubmed/36684818 http://dx.doi.org/10.1016/j.vas.2023.100286 |