Research progress of abnormal lactate metabolism and lactate modification in immunotherapy of hepatocellular carcinoma

Tumors meet their energy, biosynthesis, and redox demands through metabolic reprogramming. This metabolic abnormality results in elevated levels of metabolites, particularly lactate, in the tumor microenvironment. Immune cell reprogramming and cellular plasticity mediated by lactate and lactylation...

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Detalles Bibliográficos
Autores principales: Xu, Yiwei, Hao, Xiaodong, Ren, Yidan, Xu, Qinchen, Liu, Xiaoyan, Song, Shuliang, Wang, Yunshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853001/
https://www.ncbi.nlm.nih.gov/pubmed/36686771
http://dx.doi.org/10.3389/fonc.2022.1063423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853001/
https://www.ncbi.nlm.nih.gov/pubmed/36686771
http://dx.doi.org/10.3389/fonc.2022.1063423

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