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Research progress of abnormal lactate metabolism and lactate modification in immunotherapy of hepatocellular carcinoma
Tumors meet their energy, biosynthesis, and redox demands through metabolic reprogramming. This metabolic abnormality results in elevated levels of metabolites, particularly lactate, in the tumor microenvironment. Immune cell reprogramming and cellular plasticity mediated by lactate and lactylation...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853001/ https://www.ncbi.nlm.nih.gov/pubmed/36686771 http://dx.doi.org/10.3389/fonc.2022.1063423 |