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Tumor treatment by pHLIP-targeted antigen delivery

Targeted antigen delivery allows activation of the immune system to kill cancer cells. Here we report the targeted delivery of various epitopes, including a peptide, a small molecule, and a sugar, to tumors by pH Low Insertion Peptides (pHLIPs), which respond to surface acidity and insert to span th...

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Detalles Bibliográficos
Autores principales: DuPont, Michael, Visca, Hannah, Moshnikova, Anna, Engelman, Donald M., Reshetnyak, Yana K., Andreev, Oleg A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853002/
https://www.ncbi.nlm.nih.gov/pubmed/36686229
http://dx.doi.org/10.3389/fbioe.2022.1082290