Ticagrelor reduces doxorubicin-induced pyroptosis of rat cardiomyocytes by targeting GSK-3β/caspase-1

Doxorubicin (Dox) is a widely used clinical drug whose cardiotoxicity cannot be ignored. Pyroptosis (inflammatory cell death) has gradually gained attention in the context of Dox-induced cardiotoxicity. In addition to the inhibition of platelet activation by ticagrelor, little is known about its oth...

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Detalles Bibliográficos
Autores principales: Wang, Shu-hui, Sun, Meng-jin, Ding, Si-yue, Liu, Chun-li, Wang, Jing-min, Han, Sheng-na, Lin, Xi, Li, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853199/
https://www.ncbi.nlm.nih.gov/pubmed/36684601
http://dx.doi.org/10.3389/fcvm.2022.1090601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853199/
https://www.ncbi.nlm.nih.gov/pubmed/36684601
http://dx.doi.org/10.3389/fcvm.2022.1090601

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