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SARS-CoV-2 delta (B.1.617.2) spike protein adjuvanted with Alum-3M-052 enhances antibody production and neutralization ability

BACKGROUND: Optimizing adjuvant is one of the critical methods to improve the vaccine. 3M-052, a novel TLR7/8 agonist which was designed for slow dissemination at the injection site, has a potential as adjuvant, but its performance as a vaccine adjuvant for SARS-CoV-2 (B.1.617.2) spike protein has n...

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Detalles Bibliográficos
Autores principales: Huang, Hong, Zhou, Zhongcheng, Xiong, Xinxin, Liu, Zhihai, Zheng, Xiaoxue, Quan, Qingli, Yu, Meixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853420/
https://www.ncbi.nlm.nih.gov/pubmed/36684881
http://dx.doi.org/10.3389/fpubh.2022.976686