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Identification of the osteoarthritis signature gene PDK1 by machine learning and its regulatory mechanisms on chondrocyte autophagy and apoptosis

BACKGROUND: Osteoarthritis (OA) is a degenerative joint disease frequently diagnosed in the elderly and middle-aged population. However, its specific pathogenesis has not been clarified. This study aimed to identify biomarkers for OA diagnosis and elucidate their potential mechanisms for restoring O...

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Detalles Bibliográficos
Autores principales: Meng, Jinzhi, Du, Huawei, Lv, Haiyuan, Lu, Jinfeng, Li, Jia, Yao, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853447/
https://www.ncbi.nlm.nih.gov/pubmed/36685513
http://dx.doi.org/10.3389/fimmu.2022.1072526