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Identification of therapeutic targets for osteosarcoma by integrating single-cell RNA sequencing and network pharmacology

Background: Osteosarcoma (OS) is a common primary tumor with extensive heterogeneity. In this study, we used single-cell RNA sequencing (scRNA-seq) and network pharmacology to analyze effective targets for Osteosarcoma treatment. Methods: The cell heterogeneity of the Osteosarcoma single-cell datase...

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Detalles Bibliográficos
Autores principales: Wang, Yan, Qin, Di, Gao, Yiyao, Zhang, Yunxin, Liu, Yao, Huang, Lihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853455/
https://www.ncbi.nlm.nih.gov/pubmed/36686663
http://dx.doi.org/10.3389/fphar.2022.1098800