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Machine learning identifies T cell receptor repertoire signatures associated with COVID-19 severity

T cell receptor (TCR) repertoires are critical for antiviral immunity. Determining the TCR repertoire composition, diversity, and dynamics and how they change during viral infection can inform the molecular specificity of host responses to viruses such as SARS-CoV-2. To determine signatures associat...

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Detalles Bibliográficos
Autores principales: Park, Jonathan J., Lee, Kyoung A V., Lam, Stanley Z., Moon, Katherine S., Fang, Zhenhao, Chen, Sidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853487/
https://www.ncbi.nlm.nih.gov/pubmed/36670287
http://dx.doi.org/10.1038/s42003-023-04447-4