Late-stage functionalization of 5-nitrofurans derivatives and their antibacterial activities

Structure modification of drugs is a reliable way to optimize lead compounds, among which the most striking and direct method is late-stage functionalization (LSF). Here, we employed the Cu-catalyzed C–H LSF to modify 5-nitrofuran drugs. A series of modifications have been carried out including hydr...

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Detalles Bibliográficos
Autores principales: Chen, Geshuyi, Chang, Zhe, Yuan, Pei, Wang, Si, Yang, Yongxiu, Liang, Xiaolei, Zhao, Depeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853512/
https://www.ncbi.nlm.nih.gov/pubmed/36756397
http://dx.doi.org/10.1039/d2ra07676d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853512/
https://www.ncbi.nlm.nih.gov/pubmed/36756397
http://dx.doi.org/10.1039/d2ra07676d

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