Adenosine-Dependent Activation Mechanism of Prodrugs Targeting an Aminoacyl-tRNA Synthetase

[Image: see text] Prodrugs have little or no pharmacological activity and are converted to active drugs in the body by enzymes, metabolic reactions, or through human-controlled actions. However, prodrugs promoting their chemical bioconversion without any of these processes have not been reported bef...

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Detalles Bibliográficos
Autores principales: Hoffmann, Guillaume, Le Gorrec, Madalen, Mestdach, Emeline, Cusack, Stephen, Salmon, Loïc, Jensen, Malene Ringkjøbing, Palencia, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853866/
https://www.ncbi.nlm.nih.gov/pubmed/36599057
http://dx.doi.org/10.1021/jacs.2c04808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853866/
https://www.ncbi.nlm.nih.gov/pubmed/36599057
http://dx.doi.org/10.1021/jacs.2c04808

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