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Using magnetic mesoporous silica nanoparticles armed with EpCAM aptamer as an efficient platform for specific delivery of 5-fluorouracil to colorectal cancer cells

Background: Theranostic nanoparticles with both imaging and therapeutic capacities are highly promising in successful diagnosis and treatment of advanced cancers. Methods: Here, we developed magnetic mesoporous silica nanoparticles (MSNs) loaded with 5-fluorouracil (5-FU) and surface-decorated with...

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Detalles Bibliográficos
Autores principales: Kamil Mohammad Al-Mosawi, Aseel, Bahrami, Ahmad Reza, Nekooei, Sirous, Saljooghi, Amir Sh., Matin, Maryam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853966/
https://www.ncbi.nlm.nih.gov/pubmed/36686226
http://dx.doi.org/10.3389/fbioe.2022.1095837