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PROPERTY: study protocol for a randomized, double-blind, multicenter placebo-controlled trial assessing neurotoxicity in patients with metastatic gastrointestinal cancer taking PHYCOCARE® during oxaliplatin-based chemotherapy

BACKGROUND: Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most common adverse effects of antineoplastic agents, ranging in prevalence from 19% to over 85%. Clinically, CIPN is a predominantly sensory neuropathy that may be accompanied by motor and autonomic changes of varying inten...

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Detalles Bibliográficos
Autores principales: Le Gouill-Jaijarat, Christele, Péréon, Yann, Leroy, Maxime, Lépine, Olivier, Loloum, Aymeric, Peluchon, Claire, Volteau, Christelle, Martineau, Anne-Sophie, Korner, Simon, Perrault, Caroline, Benmaziane, Asmahane, Girot, Paul, Petorin, Caroline, Perret, Clément, Ligeza-Poisson, Catherine, Mayeur, Didier, Flet, Laurent, Chiffoleau, Anne, Poinas, Alexandra, Bennouna, Jaafar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854012/
https://www.ncbi.nlm.nih.gov/pubmed/36670495
http://dx.doi.org/10.1186/s13063-023-07071-z