PDZD8-deficient mice manifest behavioral abnormalities related to emotion, cognition, and adaptation due to dyslipidemia in the brain

Although dyslipidemia in the brain has been implicated in neurodegenerative disorders, the molecular mechanisms underlying its pathogenesis have been largely unclear. PDZD8 is a lipid transfer protein and mice deficient in PDZD8 (PDZD8-KO mice) manifest abnormal accumulation of cholesteryl esters (C...

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Detalles Bibliográficos
Autores principales: Kurihara, Yuji, Mitsunari, Kotone, Mukae, Nagi, Shoji, Hirotaka, Miyakawa, Tsuyoshi, Shirane, Michiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854033/
https://www.ncbi.nlm.nih.gov/pubmed/36658656
http://dx.doi.org/10.1186/s13041-023-01002-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854033/
https://www.ncbi.nlm.nih.gov/pubmed/36658656
http://dx.doi.org/10.1186/s13041-023-01002-4

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