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HMGB1 mediates lipopolysaccharide-induced macrophage autophagy and pyroptosis

Autophagy and pyroptosis of macrophages play important protective or detrimental roles in sepsis. However, the underlying mechanisms remain unclear. High mobility group box protein 1 (HMGB1) is associated with both pyroptosis and autophagy. lipopolysaccharide (LPS) is an important pathogenic factor...

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Detalles Bibliográficos
Autores principales: Shang, Jiawei, Zhao, Feng, Cao, Yongmei, Ping, Feng, Wang, Wei, Li, Yingchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854035/
https://www.ncbi.nlm.nih.gov/pubmed/36658496
http://dx.doi.org/10.1186/s12860-023-00464-7