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Hypofucosylation of Unc5b regulated by Fut8 enhances macrophage emigration and prevents atherosclerosis

BACKGROUND: Atherosclerosis (AS) is the leading underlying cause of the majority of clinical cardiovascular events. Retention of foamy macrophages in plaques is the main factor initiating and promoting the atherosclerotic process. Our previous work showed that ox-LDL induced macrophage retention in...

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Detalles Bibliográficos
Autores principales: Yang, Xi, Ma, Limei, Zhang, Jun, Chen, Linmu, Zou, Zhen, Shen, Di, He, Hui, Zhang, Lei, Chen, Jun, Yuan, Zhiyi, Qin, Xia, Yu, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854080/
https://www.ncbi.nlm.nih.gov/pubmed/36670464
http://dx.doi.org/10.1186/s13578-023-00959-y