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Neural network‐derived Potts models for structure‐based protein design using backbone atomic coordinates and tertiary motifs
Designing novel proteins to perform desired functions, such as binding or catalysis, is a major goal in synthetic biology. A variety of computational approaches can aid in this task. An energy‐based framework rooted in the sequence‐structure statistics of tertiary motifs (TERMs) can be used for sequ...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Inc.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854172/ https://www.ncbi.nlm.nih.gov/pubmed/36564857 http://dx.doi.org/10.1002/pro.4554 |