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RNA–DNA hybrid nano-materials for highly efficient and long lasting RNA interference effect

In attempts to effectively improve RNAi function, we herein report a new RNAi approach using X-shaped RDNA and Dgel (RNA interfering DNA hydrogel, Ri-Dgel). X-shaped RDNA is a 4 branched nanostructure which was composed of three dsDNA branches and one dsRNA branch, and the structure was made by anne...

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Detalles Bibliográficos
Autores principales: Kim, Joung Sug, Park, Junghyun, Choi, Jang Hyeon, Kang, Seungjae, Park, Nokyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854246/
https://www.ncbi.nlm.nih.gov/pubmed/36756454
http://dx.doi.org/10.1039/d2ra06249f