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Experimental evidence for CH⋯π interaction-mediated stabilization of the square form in phenylglycine-incorporated ascidiacyclamide

Ascidiacyclamide [cyclo(-Ile-oxazoline-D-Val-thiazole-)(2)] is a cytotoxic cyclic peptide from ascidian. We examined the potential of the CH⋯π interaction at the diagonal position of ascidiacyclamide by comparing the interactions of Ile, Val, Abu (2-aminobutyric acid) or Ala with Ile, Chg (cyclohexy...

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Detalles Bibliográficos
Autores principales: Asano, Akiko, Minoura, Katsuhiko, Yamada, Takeshi, Doi, Mitsunobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854340/
https://www.ncbi.nlm.nih.gov/pubmed/36741171
http://dx.doi.org/10.1039/d2ra07063d