Solithromycin inhibits IL-13-induced goblet cell hyperplasia and MUC5AC, CLCA1, and ANO1 in human bronchial epithelial cells

Solithromycin is a novel fluoroketolide antibiotic belonging to the class of macrolide antibiotics. Activation of the interleukin (IL)-13 receptor leads to STAT6 activation and subsequent induction of SAM pointed domain containing ETS transcription factor (SPDEF), chloride channel accessory 1 (CLCA1...

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Detalles Bibliográficos
Autores principales: Kimura, Yasuhiro, Shinoda, Masahiro, Shinkai, Masaharu, Kaneko, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Drugs and Devices
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854378/
https://www.ncbi.nlm.nih.gov/pubmed/36684665
http://dx.doi.org/10.7717/peerj.14695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854378/
https://www.ncbi.nlm.nih.gov/pubmed/36684665
http://dx.doi.org/10.7717/peerj.14695

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