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The superantigens SpeC and TSST-1 specifically activate TRBV12-3/12-4(+) memory T cells

Severe bacterial or viral infections can induce a state of immune hyperactivation that can culminate in a potentially lethal cytokine storm. The classic example is toxic shock syndrome, a life-threatening complication of Staphylococcus aureus or Streptococcus pyogenes infection, which is driven by p...

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Detalles Bibliográficos
Autores principales: Shepherd, Freya R., Davies, Kate, Miners, Kelly L., Llewellyn-Lacey, Sian, Kollnberger, Simon, Redman, James E., Grant, Melissa M., Ladell, Kristin, Price, David A., McLaren, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854414/
https://www.ncbi.nlm.nih.gov/pubmed/36670205
http://dx.doi.org/10.1038/s42003-023-04420-1