Dynamic Metabolic and Transcriptional Responses of Proteasome-Inhibited Neurons

HIGHLIGHTS: What are the main findings? Detailed early neuronal response to the proteasome inhibitor MG-132. Determination of sequence of events using multi-time-point multi-omics. Recording of neuronal counter-regulations to stress over time. Observation of rapid metabolic effects following proteas...

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Detalles Bibliográficos
Autores principales: Suciu, Ilinca, Delp, Johannes, Gutbier, Simon, Ückert, Anna-Katharina, Spreng, Anna-Sophie, Eberhard, Philipp, Karreman, Christiaan, Schreiber, Falk, Madjar, Katrin, Rahnenführer, Jörg, Celardo, Ivana, Amelio, Ivano, Leist, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854434/
https://www.ncbi.nlm.nih.gov/pubmed/36671027
http://dx.doi.org/10.3390/antiox12010164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854434/
https://www.ncbi.nlm.nih.gov/pubmed/36671027
http://dx.doi.org/10.3390/antiox12010164

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