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Reduced Ribose-5-Phosphate Isomerase A-1 Expression in Specific Neurons and Time Points Promotes Longevity in Caenorhabditis elegans

Deregulation of redox homeostasis is often associated with an accelerated aging process. Ribose-5-phosphate isomerase A (RPIA) mediates redox homeostasis in the pentose phosphate pathway (PPP). Our previous study demonstrated that Rpi knockdown boosts the healthspan in Drosophila. However, whether t...

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Detalles Bibliográficos
Autores principales: Shen, Wen-Chi, Yuh, Chiou-Hwa, Lu, Yu-Ting, Lin, Yen-Hung, Ching, Tsui-Ting, Wang, Chao-Yung, Wang, Horng-Dar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854458/
https://www.ncbi.nlm.nih.gov/pubmed/36670987
http://dx.doi.org/10.3390/antiox12010124