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Selective Pharmacological Inhibition of NOX2 by GSK2795039 Improves Bladder Dysfunction in Cyclophosphamide-Induced Cystitis in Mice

Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic inflammatory disease without consistently effective treatment. Among the many mediators implicated in cystitis, the overproduction of reactive oxygen species (ROS) seems to play a key role, although the main source of ROS remains uncl...

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Detalles Bibliográficos
Autores principales: de Oliveira, Mariana G., Monica, Fabíola Z., Passos, Gabriela R., Victorio, Jamaira A., Davel, Ana Paula, Oliveira, Anna Lethicia Lima, Parada, Carlos A., D’Ancona, Carlos A. L., Hill, Warren G., Antunes, Edson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854480/
https://www.ncbi.nlm.nih.gov/pubmed/36670953
http://dx.doi.org/10.3390/antiox12010092