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Dimethyl Fumarate Protects Retinal Pigment Epithelium from Blue Light-Induced Oxidative Damage via the Nrf2 Pathway

The purpose of this study is to investigate the protective effect of dimethyl fumarate (DMF), the methyl-ester of fumaric acid, against blue-light (BL) exposure in retinal pigment epithelial (RPE) cells. ARPE-19 cells, a human RPE cell line, were cultured with DMF followed by exposure to BL. Reactiv...

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Detalles Bibliográficos
Autores principales: Shimizu, Hideyuki, Takayama, Kei, Yamada, Kazuhisa, Suzumura, Ayana, Sato, Tomohito, Nishio, Yoshiaki, Ito, Masataka, Ushida, Hiroaki, Nishiguchi, Koji M, Takeuchi, Masaru, Kaneko, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854498/
https://www.ncbi.nlm.nih.gov/pubmed/36670906
http://dx.doi.org/10.3390/antiox12010045