QSAR Studies, Molecular Docking, Molecular Dynamics, Synthesis, and Biological Evaluation of Novel Quinolinone-Based Thiosemicarbazones against Mycobacterium tuberculosis

In this study, a series of novel quinolinone-based thiosemicarbazones were designed in silico and their activities tested in vitro against Mycobacterium tuberculosis (M. tuberculosis). Quantitative structure-activity relationship (QSAR) studies were performed using quinolinone and thiosemicarbazide...

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Detalles Bibliográficos
Autores principales: Valencia, Jhesua, Rubio, Vivian, Puerto, Gloria, Vasquez, Luisa, Bernal, Anthony, Mora, José R., Cuesta, Sebastian A., Paz, José Luis, Insuasty, Braulio, Abonia, Rodrigo, Quiroga, Jairo, Insuasty, Alberto, Coneo, Andres, Vidal, Oscar, Márquez, Edgar, Insuasty, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854539/
https://www.ncbi.nlm.nih.gov/pubmed/36671262
http://dx.doi.org/10.3390/antibiotics12010061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854539/
https://www.ncbi.nlm.nih.gov/pubmed/36671262
http://dx.doi.org/10.3390/antibiotics12010061

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