The Xanthine Oxidase Inhibitor Febuxostat Suppresses Adipogenesis and Activates Nrf2

Xanthine oxidoreductase (XOR) is a rate-limiting enzyme in purine catabolism that acts as a novel regulator of adipogenesis. In pathological states, xanthine oxidoreductase activity increases to produce excess reactive oxygen species (ROS). The nuclear factor erythroid 2-related factor 2 (Nrf2) is a...

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Detalles Bibliográficos
Autores principales: Higa, Yoshiki, Hiasa, Masahiro, Tenshin, Hirofumi, Nakaue, Emiko, Tanaka, Mariko, Kim, Sooha, Nakagawa, Motosumi, Shimizu, So, Tanimoto, Kotaro, Teramachi, Jumpei, Harada, Takeshi, Oda, Asuka, Oura, Masahiro, Sogabe, Kimiko, Hara, Tomoyo, Sumitani, Ryohei, Maruhashi, Tomoko, Yamagami, Hiroki, Endo, Itsuro, Matsumoto, Toshio, Tanaka, Eiji, Abe, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854541/
https://www.ncbi.nlm.nih.gov/pubmed/36670994
http://dx.doi.org/10.3390/antiox12010133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854541/
https://www.ncbi.nlm.nih.gov/pubmed/36670994
http://dx.doi.org/10.3390/antiox12010133

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