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Bilirubin Levels Are Negatively Correlated with Adiposity in Obese Men and Women, and Its Catabolized Product, Urobilin, Is Positively Associated with Insulin Resistance

Bilirubin levels in obese humans and rodents have been shown to be lower than in their lean counterparts. Some studies have proposed that the glucuronyl UGT1A1 enzyme that clears bilirubin from the blood increases in the liver with obesity. UGT1A1 clearance of bilirubin allows more conjugated biliru...

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Detalles Bibliográficos
Autores principales: Kipp, Zachary A., Xu, Mei, Bates, Evelyn A., Lee, Wang-Hsin, Kern, Philip A., Hinds, Terry D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854555/
https://www.ncbi.nlm.nih.gov/pubmed/36671031
http://dx.doi.org/10.3390/antiox12010170