Baicalein Attenuates Brain Iron Accumulation through Protecting Aconitase 1 from Oxidative Stress in Rotenone-Induced Parkinson’s Disease in Rats

Aconitase 1 (ACO1) links oxidative stress and iron accumulation in Parkinson’s disease (PD). ACO1 loses its aconitase activity and turns into iron regulatory protein 1 (IRP1) upon oxidative stress. IRP1 plays an important role in the accumulation of intracellular iron. Baicalein is a flavonoid isola...

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Detalles Bibliográficos
Autores principales: Liu, Run-Zhe, Zhang, Sen, Zhang, Wen, Zhao, Xiao-Yue, Du, Guan-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854573/
https://www.ncbi.nlm.nih.gov/pubmed/36670874
http://dx.doi.org/10.3390/antiox12010012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854573/
https://www.ncbi.nlm.nih.gov/pubmed/36670874
http://dx.doi.org/10.3390/antiox12010012

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