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Baicalein Attenuates Brain Iron Accumulation through Protecting Aconitase 1 from Oxidative Stress in Rotenone-Induced Parkinson’s Disease in Rats

Aconitase 1 (ACO1) links oxidative stress and iron accumulation in Parkinson’s disease (PD). ACO1 loses its aconitase activity and turns into iron regulatory protein 1 (IRP1) upon oxidative stress. IRP1 plays an important role in the accumulation of intracellular iron. Baicalein is a flavonoid isola...

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Detalles Bibliográficos
Autores principales:	Liu, Run-Zhe, Zhang, Sen, Zhang, Wen, Zhao, Xiao-Yue, Du, Guan-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854573/ https://www.ncbi.nlm.nih.gov/pubmed/36670874 http://dx.doi.org/10.3390/antiox12010012

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