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Fundamental Role of Pentose Phosphate Pathway within the Endoplasmic Reticulum in Glutamine Addiction of Triple-Negative Breast Cancer Cells

Cancer utilization of large glutamine equivalents contributes to diverging glucose-6-P flux toward the pentose phosphate shunt (PPP) to feed the building blocks and the antioxidant responses of rapidly proliferating cells. In addition to the well-acknowledged cytosolic pathway, cancer cells also run...

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Detalles Bibliográficos
Autores principales: Marini, Cecilia, Cossu, Vanessa, Carta, Sonia, Greotti, Elisa, Gaglio, Daniela, Bertola, Nadia, Chiesa, Sabrina, Bruno, Silvia, Vitale, Francesca, Bonanomi, Marcella, Porro, Danilo, Riondato, Mattia, Orengo, Anna Maria, Bauckneht, Matteo, Morbelli, Silvia, Ravera, Silvia, Sambuceti, Gianmario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854646/
https://www.ncbi.nlm.nih.gov/pubmed/36670904
http://dx.doi.org/10.3390/antiox12010043