Adipose-Derived Mesenchymal Stem Cells Inhibit JNK-Mediated Mitochondrial Retrograde Pathway to Alleviate Acetaminophen-Induced Liver Injury

Acetaminophen (APAP) is the major cause of drug-induced liver injury, with limited treatment options. APAP overdose invokes excessive oxidative stress that triggers mitochondria-to-nucleus retrograde pathways, contributing to APAP-induced liver injury (AILI). Mesenchymal stem cell therapy is a promi...

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Detalles Bibliográficos
Autores principales: Cen, Yelei, Lou, Guohua, Qi, Jinjin, Li, Minwei, Zheng, Min, Liu, Yanning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854665/
https://www.ncbi.nlm.nih.gov/pubmed/36671020
http://dx.doi.org/10.3390/antiox12010158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854665/
https://www.ncbi.nlm.nih.gov/pubmed/36671020
http://dx.doi.org/10.3390/antiox12010158

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