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Dihydromyricetin Attenuates Diabetic Cardiomyopathy by Inhibiting Oxidative Stress, Inflammation and Necroptosis via Sirtuin 3 Activation

Dihydromyricetin (DHY), the main flavonoid component in Ampelopsis grossedentata, has important benefits for health. The present study aimed to investigate the exact effects and possible mechanisms of DHY on diabetic cardiomyopathy (DCM). Male C57BL/6 mice and sirtuin 3 (SIRT3) knockout (SIRT3-KO) m...

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Detalles Bibliográficos
Autores principales: Chen, Yun, Zheng, Yangyang, Chen, Ruixiang, Shen, Jieru, Zhang, Shuping, Gu, Yunhui, Shi, Jiahai, Meng, Guoliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854700/
https://www.ncbi.nlm.nih.gov/pubmed/36671063
http://dx.doi.org/10.3390/antiox12010200