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Antibiofilm and Anti-Quorum-Sensing Activities of Novel Pyrazole and Pyrazolo[1,5-a]pyrimidine Derivatives as Carbonic Anhydrase I and II Inhibitors: Design, Synthesis, Radiosterilization, and Molecular Docking Studies

Nowadays, searching for new anti-infective agents with diverse mechanisms of action has become necessary. In this study, 16 pyrazole and pyrazolo[1,5-a]pyrimidine derivatives were synthesized and assessed for their preliminary antibacterial and antibiofilm activities. All these derivatives were init...

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Detalles Bibliográficos
Autores principales: Ragab, Ahmed, Fouad, Sawsan A., Ammar, Yousry A., Aboul-Magd, Dina S., Abusaif, Moustafa S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854762/
https://www.ncbi.nlm.nih.gov/pubmed/36671329
http://dx.doi.org/10.3390/antibiotics12010128