Cleavage of Occludin by Cigarette Smoke-Elicited Cathepsin S Increases Permeability of Lung Epithelial Cells

Background. Chronic obstructive pulmonary disease (COPD) is an irreversible disease mainly caused by smoking. COPD is characterized by emphysema and chronic bronchitis associated with enhanced epithelial permeability. Hypothesis. Lung biopsies from smokers revealed a decreased expression level of oc...

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Detalles Bibliográficos
Autores principales: Bigot, Paul, Chesseron, Simon, Saidi, Ahlame, Sizaret, Damien, Parent, Christelle, Petit-Courty, Agnès, Courty, Yves, Lecaille, Fabien, Lalmanach, Gilles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854811/
https://www.ncbi.nlm.nih.gov/pubmed/36670867
http://dx.doi.org/10.3390/antiox12010005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854811/
https://www.ncbi.nlm.nih.gov/pubmed/36670867
http://dx.doi.org/10.3390/antiox12010005

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