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Structure–Activity Relationship Studies of Substitutions of Cationic Amino Acid Residues on Antimicrobial Peptides

Antimicrobial peptides (AMPs) have received considerable attention as next-generation drugs for infectious diseases. Amphipathicity and the formation of a stabilized secondary structure are required to exert their antimicrobial activity by insertion into the microbial membrane, resulting in lysis of...

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Detalles Bibliográficos
Autores principales: Takada, Mayu, Ito, Takahito, Kurashima, Megumi, Matsunaga, Natsumi, Demizu, Yosuke, Misawa, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854868/
https://www.ncbi.nlm.nih.gov/pubmed/36671220
http://dx.doi.org/10.3390/antibiotics12010019