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Structure–Activity Relationship Studies of Substitutions of Cationic Amino Acid Residues on Antimicrobial Peptides
Antimicrobial peptides (AMPs) have received considerable attention as next-generation drugs for infectious diseases. Amphipathicity and the formation of a stabilized secondary structure are required to exert their antimicrobial activity by insertion into the microbial membrane, resulting in lysis of...
Autores principales: | Takada, Mayu, Ito, Takahito, Kurashima, Megumi, Matsunaga, Natsumi, Demizu, Yosuke, Misawa, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854868/ https://www.ncbi.nlm.nih.gov/pubmed/36671220 http://dx.doi.org/10.3390/antibiotics12010019 |
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