Semisynthetic Amides of Amphotericin B and Nystatin A(1): A Comparative Study of In Vitro Activity/Toxicity Ratio in Relation to Selectivity to Ergosterol Membranes

Polyene antifungal amphotericin B (AmB) has been used for over 60 years, and remains a valuable clinical treatment for systemic mycoses, due to its broad antifungal activity and low rate of emerging resistance. There is no consensus on how exactly it kills fungal cells but it is certain that AmB and...

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Detalles Bibliográficos
Autores principales: Tevyashova, Anna, Efimova, Svetlana, Alexandrov, Alexander, Omelchuk, Olga, Ghazy, Eslam, Bychkova, Elena, Zatonsky, Georgy, Grammatikova, Natalia, Dezhenkova, Lyubov, Solovieva, Svetlana, Ostroumova, Olga, Shchekotikhin, Andrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854944/
https://www.ncbi.nlm.nih.gov/pubmed/36671352
http://dx.doi.org/10.3390/antibiotics12010151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854944/
https://www.ncbi.nlm.nih.gov/pubmed/36671352
http://dx.doi.org/10.3390/antibiotics12010151

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