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Metabolic Profiling and Investigation of the Modulatory Effect of Fagonia cretica L. Aerial Parts on Hepatic CYP3A4 and UGT2B7 Enzymes in Streptozotocin—Induced Diabetic Model

Drug-metabolizing enzymes are either boosted or suppressed by diabetes mellitus. This research was designed to explore Fagonia cretica L. aerial parts’ impact on CYP3A4 and UGT2B7 activity and their mRNA expression in diabetic rats. Fagonia cretica (F. cretica) dried powder was sequentially extracte...

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Detalles Bibliográficos
Autores principales: Kamran, Shahzad, Anwar, Rukhsana, Noor, Afifa, Ullah, Muhammad Ihsan, Bagalagel, Alaa A., Aldurdunji, Mohammed M., Ishtiaq, Saiqa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854966/
https://www.ncbi.nlm.nih.gov/pubmed/36670981
http://dx.doi.org/10.3390/antiox12010119