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P2X7 Is Involved in the Mouse Retinal Degeneration via the Coordinated Actions in Different Retinal Cell Types

Adenosine triphosphate (ATP) released from dying cells with high concentrations is sensed as a danger signal by the P2X7 receptor. Sodium iodate (NaIO(3)) is an oxidative toxic agent, and its retinal toxicity has been used as the model of dry age-related macular degeneration (AMD). In this study, we...

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Detalles Bibliográficos
Autores principales: Sekar, Ponarulselvam, Hsiao, George, Chen, Yuan-Shen, Lin, Wan-Wan, Chan, Chi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854982/
https://www.ncbi.nlm.nih.gov/pubmed/36671003
http://dx.doi.org/10.3390/antiox12010141