Cargando…
P2X7 Is Involved in the Mouse Retinal Degeneration via the Coordinated Actions in Different Retinal Cell Types
Adenosine triphosphate (ATP) released from dying cells with high concentrations is sensed as a danger signal by the P2X7 receptor. Sodium iodate (NaIO(3)) is an oxidative toxic agent, and its retinal toxicity has been used as the model of dry age-related macular degeneration (AMD). In this study, we...
Autores principales: | Sekar, Ponarulselvam, Hsiao, George, Chen, Yuan-Shen, Lin, Wan-Wan, Chan, Chi-Ming |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854982/ https://www.ncbi.nlm.nih.gov/pubmed/36671003 http://dx.doi.org/10.3390/antiox12010141 |
Ejemplares similares
-
Different Effects of Metformin and A769662 on Sodium Iodate-Induced Cytotoxicity in Retinal Pigment Epithelial Cells: Distinct Actions on Mitochondrial Fission and Respiration
por: Chan, Chi-Ming, et al.
Publicado: (2020) -
Coordinate effects of P2X7 and extracellular acidification in microglial cells
por: Sekar, Ponarulselvam, et al.
Publicado: (2018) -
Metformin inhibits methylglyoxal-induced retinal pigment epithelial cell death and retinopathy via AMPK-dependent mechanisms: Reversing mitochondrial dysfunction and upregulating glyoxalase 1
por: Sekar, Ponarulselvam, et al.
Publicado: (2023) -
Reactive oxygen species-dependent mitochondrial dynamics and autophagy confer protective effects in retinal pigment epithelial cells against sodium iodate-induced cell death
por: Chan, Chi-Ming, et al.
Publicado: (2019) -
Correction to: Reactive oxygen species-dependent mitochondrial dynamics and autophagy confer protective effects in retinal pigment epithelial cells against sodium iodate-induced cell death
por: Chan, Chi-Ming, et al.
Publicado: (2019)