Use of High-Dose Nebulized Colistimethate in Patients with Colistin-Only Susceptible Acinetobacter baumannii VAP: Clinical, Pharmacokinetic and Microbiome Features

(1) Background: Colistin-only susceptible (COS) Acinetobacter baumannii (AB) ventilator-associated pneumonia (VAP) represents a clinical challenge in the Intensive Care Unit (ICU) due to the negligible lung diffusion of this molecule and the low-grade evidence on efficacy of its nebulization. (2) Me...

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Detalles Bibliográficos
Autores principales: De Pascale, Gennaro, Pintaudi, Gabriele, Lisi, Lucia, De Maio, Flavio, Cutuli, Salvatore Lucio, Tanzarella, Eloisa Sofia, Carelli, Simone, Lombardi, Gianmarco, Cesarano, Melania, Gennenzi, Veronica, Ciotti, Gabriella Maria Pia, Grieco, Domenico Luca, Posteraro, Brunella, Sanguinetti, Maurizio, Navarra, Pierluigi, Antonelli, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855104/
https://www.ncbi.nlm.nih.gov/pubmed/36671325
http://dx.doi.org/10.3390/antibiotics12010125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855104/
https://www.ncbi.nlm.nih.gov/pubmed/36671325
http://dx.doi.org/10.3390/antibiotics12010125

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