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YPL-001 Shows Various Beneficial Effects against Cigarette Smoke Extract-Induced Emphysema Formation: Anti-Inflammatory, Anti-Oxidative, and Anti-Apoptotic Effects

Inflammation, oxidative stress, and apoptosis are thought to be important causes of chronic obstructive pulmonary disease (COPD). We investigated the effect of YPL-001 (under phase 2a study, ClinicalTrials.gov identifier NCT02272634), a drug derived from Pseudolysimachion rotundum var. subintegrum,...

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Detalles Bibliográficos
Autores principales: Lee, Kyoung-Hee, Woo, Jisu, Kim, Jiyeon, Lee, Chang-Hoon, Yoo, Chul-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855183/
https://www.ncbi.nlm.nih.gov/pubmed/36670877
http://dx.doi.org/10.3390/antiox12010015