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IGF2: A Role in Metastasis and Tumor Evasion from Immune Surveillance?

Insulin-like growth factor 2 (IGF2) is upregulated in both childhood and adult malignancies. Its overexpression is associated with resistance to chemotherapy and worse prognosis. However, our understanding of its physiological and pathological role is lagging behind what we know about IGF1. Dysregul...

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Detalles Bibliográficos
Autores principales: Belfiore, Antonino, Rapicavoli, Rosaria Valentina, Le Moli, Rosario, Lappano, Rosamaria, Morrione, Andrea, De Francesco, Ernestina Marianna, Vella, Veronica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855361/
https://www.ncbi.nlm.nih.gov/pubmed/36672737
http://dx.doi.org/10.3390/biomedicines11010229