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Proteomics of High-Grade Serous Ovarian Cancer Models Identifies Cancer-Associated Fibroblast Markers Associated with Clinical Outcomes

The tumor microenvironment has recently emerged as a critical component of high-grade serous ovarian cancer (HGSC) disease progression. Specifically, cancer-associated fibroblasts (CAFs) have been recognized as key players in various pro-oncogenic processes. Here, we use mass-spectrometry (MS) to ch...

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Detalles Bibliográficos
Autores principales: Govindarajan, Meinusha, Ignatchenko, Vladimir, Ailles, Laurie, Kislinger, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855416/
https://www.ncbi.nlm.nih.gov/pubmed/36671461
http://dx.doi.org/10.3390/biom13010075